Article
Thy-1 involvement in neurite outgrowth: perturbation by antibodies, phospholipase C, and mutation.
Developmental biology - 1 Mar 1992
Mahanthappa N K, Patterson P H
Abstract excerpt
Thy-1 is a major cell surface protein anchored in the plasma membrane of neurons and lymphocytes by a covalent glyco-phosphatidyl-inositide linkage. Despite thorough characterization of the molecule's physicochemical properties, its biological function remains elusive. In this study we demonstrate that (i) monoclonal antibodies directed against Thy-1 are capable of enhancing neurite outgrowth from sympathetic...
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