Article
Thy-1 involvement in neurite outgrowth: perturbation by antibodies, phospholipase C, and mutation.
Developmental biology - 1 Mar 1992
Mahanthappa N K, Patterson P H
Abstract excerpt
Thy-1 is a major cell surface protein anchored in the plasma membrane of neurons and lymphocytes by a covalent glyco-phosphatidyl-inositide linkage. Despite thorough characterization of the molecule's physicochemical properties, its biological function remains elusive. In this study we demonstrat...
Topics
- Adrenal Glands
- Animals
- Animals, Newborn
- Antibodies, Anti-Idiotypic
- Antigens, Surface
- Cell Membrane
- Cells, Cultured
- Ganglia, Spinal
- Membrane Glycoproteins
- Mutation
- Neurites
- Rats
- Thy-1 Antigens
- Type C Phospholipases
