Article
PTP1B regulates neurite extension mediated by cell-cell and cell-matrix adhesion molecules.
Journal of neuroscience research - 15 Jan 2001
Pathre P, Arregui C, Wampler T, Kue I, Leung T C, Lilien J, Balsamo J
Abstract excerpt
N-cadherin and beta1-integrin adhesion and signaling play important roles in growth cone adhesion and guidance. Each of these adhesion receptor systems is composed of multiprotein complexes, and both adhesion and downstream signaling events are regulated through the interaction of protein tyrosine kinases and phosphatases with many of the proteins that make up these complex systems. Work from our laboratory...
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