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Article

Cellular reservoirs for coronavirus infection of the brain in beta2-microglobulin knockout mice.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2000

Lavi E, Das Sarma J, Weiss S R

Abstract excerpt

Mouse hepatitis virus (MHV) A59 infection which causes acute encephalitis, hepatitis, and chronic demyelination, is one of the experimental models for multiple sclerosis. Previous studies showed that lethal infection of beta2-microglobulin 'knockout' (beta2M(-/-)) mice required 500-fold less virus and viral clearance was delayed as compared to infection of immunocompetent C57Bl/6 (B6) mice. To investigate the...

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Identifiers

PMID: 10023135
DOI: 10.1159/000028054
PMCID: PMC7179536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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