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Article

Characterization of sequence changes in kinetoplast DNA maxicircles of drug-resistant Leishmania.

Molecular and biochemical parasitology - 1 Dec 1992

Lee S T, Tarn C, Wang C Y

Abstract excerpt

We have compared kinetoplast DNA maxicircles of tunicamycin- and arsenite-resistant variants of repeatedly cloned Leishmania mexicana amazonensis showing DNA amplification with wild-type and arsenite-resistant variants of the same lineage that do not show DNA amplification. DNA restriction patterns and the degree of cross-hybridization between maxicircle DNA fragments of parasites displaying DNA amplification and...

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PMID: 1336569
DOI: 10.1016/0166-6851(92)90169-k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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