Article
Selection for arsenite resistance causes reversible changes in minicircle composition and kinetoplast organization in Leishmania mexicana.
Molecular and cellular biology - 1 Jan 1994
Lee S T, Liu H Y, Lee S P, Tarn C
Abstract excerpt
Certain minor minicircle sequence classes in the kinetoplast DNA (kDNA) networks of arsenite- or tunicamycin-resistant Leishmania mexicana amazonensis variants whose nuclear DNA is amplified appear to be preferentially selected to replicate (S. T. Lee, C. Tarn, and K. P. Chang, Mol. Biochem. Para...
Topics
- Animals
- Arsenites
- Cattle
- DNA Topoisomerases, Type II
- DNA, Kinetoplast
- Drug Resistance
- Genetic Variation
- Leishmania mexicana
- Microscopy, Electron