Article
Polyoma tumorigenesis in mice: evidence for dominant resistance and dominant susceptibility genes of the host.
Virology - 1 Dec 1992
Freund R, Dubensky T, Bronson R, Sotnikov A, Carroll J, Benjamin T
Abstract excerpt
We have determined the tumor responses of nine inbred mouse strains and of two F1 hybrids following inoculation with polyoma virus. The results showed wide variations in the frequencies of mice developing tumors. Correlation with H-2 haplotype were evident. C3H/BiDa mice of H-2k type were fully susceptible, while C57BL/6 mice of H-2b type were completely resistant. DBA/2 and BALB/c mice, both H-2d, were of low...
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