Article
Effects of the MHC on hormonal induction of mammary tumors and function of hypophyseal isografts in the mouse.
Immunogenetics - 1 Jan 1990
Röpcke G, Moen C J, Hart A A, Demant P
Abstract excerpt
While the role of the H-2 complex in the resistance to virally induced tumors has been extensively studied, little is known about its influence on the development of epithelial tumors of non-viral etiology, although such tumors are most prevalent in humans. Therefore, we analyzed the role of the H-2 complex in susceptibility to mammary tumors induced by hormonal stimulation from heterotopic hypophyseal isografts...
Topics
- Animals
- Estrogens
- Female
- Genetic Predisposition to Disease
- H-2 Antigens
- Haplotypes
- Major Histocompatibility Complex
- Male
- Mammary Neoplasms, Experimental
- Mice
- Mice, Inbred Strains
