Article
Pyvs: a dominantly acting gene in C3H/BiDa mice conferring susceptibility to tumor induction by polyoma virus.
Virology - 1 Sept 1993
Lukacher A E, Freund R, Carroll J P, Bronson R T, Benjamin T L
Abstract excerpt
Results in a previous report established the presence of dominant genetic factor(s) in C3H/BiDa mice which contributed to the unusually high susceptibility of this strain to polyoma virus-induced tumors (Freund et al. (1992) Virology 191, 724-731). Here we show that C57BR/cdJ mice, while identica...
Topics
- 3T3 Cells
- Animals
- Cell Transformation, Viral
- Cells, Cultured
- Crosses, Genetic
- Genes, Dominant
- Genetic Predisposition to Disease
- Immunohistochemistry
- Kidney
- Major Histocompatibility Complex
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Polyomavirus
- Receptors, Virus
- Tumor Virus Infections
