Article
Streamer F mutants and chemotaxis of Dictyostelium.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jul 1992
Newell P C, Liu G
Abstract excerpt
Streamer F mutants have been found to be useful tools for studying the pathway of signal transduction leading to chemotactic cell movement. The primary defect in these mutants is in the structural gene for the cyclic GMP specific phosphodiesterase. This defect allows a larger and prolonged peak of cyclic GMP to be formed in response to the chemotactic stimulus, cyclic AMP. This characteristic aberrant pattern of...
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