Article
The role of cGMP and the rear of the cell in Dictyostelium chemotaxis and cell streaming.
Journal of cell science - 1 Jan 2008
Veltman Douwe M, van Haastert Peter J M
Abstract excerpt
During chemotaxis, pseudopod extensions lead the cell towards the source of attractant. The role of actin-filled pseudopodia at the front of the cell is well recognized, whereas the function of the rear of the cell in chemotaxis and cell-cell interactions is less well known. Dictyostelium cell aggregation is mediated by outwardly propagating waves of extracellular cAMP that induce chemotaxis and cell-cell...
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