Article
Behavioral responses of streamer F mutants of Dictyostelium discoideum: effects of cyclic GMP on cell motility.
Journal of cell science - 1 Mar 1992
Segall J E
Abstract excerpt
Streamer F (stmF) mutants have a prolonged increase in intracellular cGMP in response to addition of the chemoattractant cAMP. The speed of movement and area of stmF cells were quantitated as the cells were stimulated with a rapid, uniform increase in extracellular cAMP. The speed of stmF cells rapidly drops as does that of the wild-type, but then requires about 300 seconds to recover. In contrast, the speed of...
Topics
- 3',5'-Cyclic-GMP Phosphodiesterases
- Animals
- Cell Aggregation
- Chemotaxis
- Cyclic AMP
- Cyclic GMP
- Dictyostelium
- Kinetics
- Mutation