Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutant analysis suggests that cyclic GMP mediates the cyclic AMP-induced Ca2+ uptake in Dictyostelium.

Journal of cell science - 1 May 1991

Menz S, Bumann J, Jaworski E, Malchow D

Abstract excerpt

Previous work has shown that streamer F (stmF) mutants of Dictyostelium discoideum exhibit prolonged chemotactic elongation in aggregation fields. The mutants carry an altered structural gene for cyclic GMP phosphodiesterase resulting in low activities of this enzyme. Chemotactic stimulation by c...

Topics

Animals
Calcium
Cyclic AMP
Cyclic GMP
Dictyostelium
Inositol 1,4,5-Trisphosphate
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1661742
DOI: 10.1242/jcs.99.1.187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1661742-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutant analysis suggests that cyclic GMP mediates the cyclic AMP-induced Ca2+ uptake in Dictyostelium.PMID 1661742Read ↗

Streamer F mutants and chemotaxis of Dictyostelium.Semantic proximity Read ↗

The role of cyclic GMP in regulating myosin during chemotaxis of Dictyostelium: evidence from a mutant lacking the normal cyclic GMP response to cyclic AMP.Semantic proximity Read ↗

Chemoattractant-stimulated calcium influx in Dictyostelium discoideum does not depend on cGMP.Semantic proximity Read ↗

Abberant chemotaxis and differentiation in Dictyostelium mutant fgdC with a defective regulation of receptor-stimulated phosphoinositidase C.Semantic proximity Read ↗

A model for cAMP-mediated cGMP response in Dictyostelium discoideum.Semantic proximity Read ↗

EGF-like peptide-enhanced cell motility in Dictyostelium functions independently of the cAMP-mediated pathway and requires active Ca2+/calmodulin signaling.Semantic proximity Read ↗

Arachidonic acid is a chemoattractant for Dictyostelium discoideum cells.Semantic proximity Read ↗

Non-chemotactic Dictyostelium discoideum mutants with altered cGMP signal transduction.Semantic proximity Read ↗

Behavioral responses of streamer F mutants of Dictyostelium discoideum: effects of cyclic GMP on cell motility.Semantic proximity Read ↗

Release of Ca2+ from the endoplasmic reticulum contributes to Ca2+ signaling in Dictyostelium discoideum.Semantic proximity Read ↗

cAMP controls cytosolic Ca2+ levels in Dictyostelium discoideum.Semantic proximity Read ↗

Chemotaxis to cAMP and slug migration in Dictyostelium both depend on migA, a BTB protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.