Article
Certain tryptophan photoproducts are inhibitors of cytochrome P450-dependent mutagenicity.
Environmental and molecular mutagenesis - 1 Jan 1992
Rannug U, Agurell E, Rannug A, Cederberg H
Abstract excerpt
Two photoproducts, derived from UV-irradiation of the amino acid L-tryptophan and with high Ah (TCDD) receptor binding affinity, were tested for genotoxic and antimutagenic effects. The two indolo[3,2-b]carbazole derivatives, with the molecular weights of 284 and 312, respectively, were tested in Saccharomyces cerevisiae strain D7 for mitotic gene conversion and reverse mutation and in strain RS112 for sister...
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