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Article

Food-derived heterocyclic amines potentiate the mutagenicity of a drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).

Mutation research - 3 Jul 1997

Watanabe-Akanuma M, Shimoi K, Kinae N, Ohta T

Abstract excerpt

We investigated the enhancing effect of heterocyclic amines on base-substitution mutations with 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) and 2-amino-3,4-dimethyl-imidazo[4,5-f]quinoline (MeIQ). We compared the mutagenicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)...

Topics

Adenosine Triphosphatases
Bacterial Proteins
Carbolines
DNA Repair
DNA-Binding Proteins
Dose-Response Relationship, Drug
Escherichia coli
Escherichia coli Proteins
Furans
Mutagenicity Tests
Mutagens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Quinolines

Source

Identifiers

PMID: 9247618
DOI: 10.1016/s0027-5107(97)00077-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9247618-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Food-derived heterocyclic amines potentiate the mutagenicity of a drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).PMID 9247618Read ↗

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