Article
Apoptosis induced by anticancer drugs.
Cancer metastasis reviews - 1 Sept 1992
Hickman J A
Abstract excerpt
Most of the cytotoxic anticancer drugs in current use have been shown to induce apoptosis in susceptible cells. The fact that disparate agents, which interact with different targets, induce cell death with some common features (endonucleolytic cleavage of DNA, changes in chromatin condensation) s...
Topics
- Animals
- Antimetabolites, Antineoplastic
- Antineoplastic Agents
- Apoptosis
- Calcium
- Cholesterol
- DNA
- Glucocorticoids
- Humans
- Phenotype
- Receptors, Glucocorticoid
- Topoisomerase I Inhibitors
