Article
Programmed cell death (apoptosis) and response to anti-cancer drugs
1 Feb 1994
Abstract excerpt
Programmed cell death (apoptosis) is a conserved, natural mechanism for the removal of redundant and unwanted cells during normal development. This article reviews the evidence that apoptosis may also control the response of tumor cells to treatment with cytostatic drugs. Whereas most clinically used anti-cancer drugs can activate late events of apoptosis (DNA degradation and morphological changes) there are...
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