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Article

Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis.

Advances in cancer research - 1 Jan 2008

Sionov Ronit Vogt, Spokoini Rachel, Kfir-Erenfeld Shlomit, Cohen Orly, Yefenof Eitan

Abstract excerpt

Glucocorticoids (GCs) are commonly used in the treatment of hematopoietic malignancies owing to their ability to induce apoptosis of these cancerous cells. Whereas some types of lymphoma and leukemia respond well to this drug, others are resistant. Also, GC-resistance gradually develops upon repeated treatments ultimately leading to refractory relapsed disease. Understanding the mechanisms regulating GC-induced...

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Identifiers

PMID: 19055945
DOI: 10.1016/S0065-230X(08)00406-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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