Article
RAR gamma 2 expression is regulated through a retinoic acid response element embedded in Sp1 sites.
Molecular and cellular biology - 1 Jul 1992
Lehmann J M, Zhang X K, Pfahl M
Abstract excerpt
At the level of transcription, all signals of the vitamin A derivative retinoic acid (RA) are mediated by the RA receptors (RARs) as well as the retinoid X receptors (RXRs). The control of expression of the various receptor subtypes and their specific isoforms appears to be strictly regulated and can be assumed to play a pivotal role during development and in the adult tissue. It has previously been shown that...
Topics
- Animals
- Base Sequence
- Binding Sites
- Carrier Proteins
- Cells, Cultured
- DNA Mutational Analysis
- Genetic Variation
- Humans
- Molecular Sequence Data
- Promoter Regions, Genetic
- Receptors, Retinoic Acid