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Article

Transcriptional co-operativity between distant retinoic acid response elements in regulation of<i>Cyp26A1</i>inducibility

8 Nov 2005

Abstract excerpt

Cyp26A1 encodes an RA (retinoic acid)-catabolizing CYP (cytochrome P450) protein that plays a critical role in regulating RA distribution in vivo. Cyp26A1 expression is inducible by RA, and the locus has previously been shown to contain a RARE (RA response element), R1, within the minimal promoter [Loudig, Babichuk, White, Abu-Abed, Mueller and Petkovich (2000) Mol. Endocrinol. 14, 1483-1497]. In the present...

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PMID: 16053444
DOI: 10.1042/bj20050874

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