Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

doi:10.1002/j.1460-2075.1991.tb07921.x

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Article

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

The EMBO journal - 1 Jan 1991

Leroy P, Krust A, Zelent A, Mendelsohn C, Garnier J M, Kastner P, Dierich A, Chambon P

Abstract excerpt

Together with the previously described mouse retinoic acid receptor alpha-1 (mRAR-alpha 1, formerly mRAR-alpha 0), we have isolated and characterized here a total of seven mRAR-alpha cDNA isoforms (mRAR-alpha 1 to alpha 7). These isoforms are generated from mRAR-alpha primary transcript(s) of a single gene by alternative splicing of at least eight different exons with the exon which encodes the amino acid...

Topics

Amino Acid Sequence
Animals
Base Sequence
Carrier Proteins
DNA
Exons
Gene Library
Genetic Variation
Humans
Mice
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligonucleotide Probes

Polymerase Chain Reaction

Promoter Regions, Genetic

RNA Splicing

RNA, Messenger

Receptors, Retinoic Acid

Sequence Homology, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 1846598
DOI: 10.1002/j.1460-2075.1991.tb07921.x
PMCID: PMC452611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1846598-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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