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Article

Synchronous and metachronous lung carcinomas: Molecular evidence for multicentricity

1 Nov 1998

Abstract excerpt

The present study is aimed to evaluate the genetic evidence for multicentricity of synchronous and metachronous multiple lung carcinomas. Nineteen cases of synchronous multiple lung carcinomas and 11 cases of metachronous multiple lung carcinomas were analyzed for p53 protein overexpression by immunohistochemistry (DO-7) and for genetic abnormality of the p53 gene by loss of heterozygosity (LOH) at chromosome 17p...

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Identifiers

PMID: 9832055
DOI: 10.1111/j.1440-1827.1998.tb03853.x

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