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In vitro establishment of tumorigenic human B-lymphoblastoid cell lines transformed by Epstein-Barr virus.

DNA and cell biology - 1 Nov 2003

Takahashi Tomoko, Kawabe Tamae, Okazaki Yuichi, Itoh Chie, Noda Keisuke, Tajima Manami, Satoh Misako, Goto Makoto, Mitsui Youji, Tahara Hidetoshi, Ide Toshinori, Furuichi Yasuhiro, Sugimoto Masanobu

Abstract excerpt

We studied tumorigenic and phenotypic characteristics of pre- and postimmortal human B-lymphoblastoid cell lines (LCLs) transformed by Epstein-Barr virus (EBV): preimmortal LCLs showed low telomerase activity and a normal diploid karyotype while postimmortal LCLs showed much higher telomerase activity and maintained a clonal aneuploidic state. Among five postimmortal LCLs tested, LCLs N0005 and N6803 formed...

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PMID: 14659045
DOI: 10.1089/104454903770946700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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