Article
A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1.
Cell - 15 May 1992
Hsu V W, Shah N, Klausner R D
Abstract excerpt
Brefeldin A (BFA) is a unique drug affecting the molecular mechanisms that regulate membrane traffic and organelle structure. BFA's ability to alter retrograde traffic from the Golgi to the endoplasmic reticulum (ER) led us to ask whether the ERD-2 retrieval receptor, proposed to return escaped E...
Topics
- Amino Acid Sequence
- Base Sequence
- Brefeldin A
- Carrier Proteins
- Cell Compartmentation
- Cloning, Molecular
- Cyclopentanes
- Endocytosis
- GTP-Binding Proteins
- Gene Expression
- Golgi Apparatus
- Humans
- Membrane Proteins
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Phenotype
- Protein Processing, Post-Translational
- Proteins