Effects of brefeldin A on the three-dimensional structure of the Golgi apparatus in a sensitive strain of Saccharomyces cerevisiae.

doi:10.1002/ar.1092410102

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Article

Effects of brefeldin A on the three-dimensional structure of the Golgi apparatus in a sensitive strain of Saccharomyces cerevisiae.

The Anatomical record - 1 Jan 1995

Rambourg A, Clermont Y, Jackson C L, Képès F

Abstract excerpt

BACKGROUND: Brefeldin A (BFA), when added to the medium of cultured mammalian cells, induces a reversible block of secretion and disrupts the Golgi apparatus whereas Golgi enzyme markers appear to redistribute into the endoplasmic reticulum (ER). It has been shown in addition that in mammalian ce...

Topics

ADP-Ribosylation Factor 1
ADP-Ribosylation Factors
Brefeldin A
Cyclopentanes
Endoplasmic Reticulum
GTP-Binding Proteins
Genes, Bacterial
Golgi Apparatus
Microscopy, Electron
Mutation
Saccharomyces cerevisiae

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