Article
The effects of gonadectomy on glucose tolerance of genetically obese (fa/fa) rats: influence of sex and genetic background.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Feb 1992
Kava R A, West D B, Lukasik V A, Wypijewski C, Wojnar Z, Johnson P R, Greenwood M R
Abstract excerpt
In both humans and rodents the occurrence and severity of obesity-associated non-insulin dependent diabetes mellitus (NIDDM) may be influenced by both gonadal hormones and genetic background. Early gonadectomy (at 3-5 days of age) of female and male Wistar diabetic fatty (WDF) rats and of male Zu...
Topics
- Animals
- Blood Glucose
- Body Weight
- Castration
- Diabetes Mellitus, Type 2
- Eating
- Female
- Genotype
- Glucose
- Glucose Tolerance Test
- Insulin