Article
The effect of a genetic variant for obesity and Type 2 Diabetes on the therapeutic potential of exercise and calorie restrictive diets in Zucker rats.
Research and theory for nursing practice - 1 Jan 2003
Metzger Bonnie L
Abstract excerpt
Obesity and Type 2 Diabetes are modern pandemics caused by unique genetic-environmental interactions and distinguished by almost universal treatment failures. Relative influences of genome and lifestyle changes on an adult onset Obesity-Type 2 diabetes phenotype were explored. Zucker rats, a recessive model of genetic obesity-Type 2 Diabetes (117 fa/fa and 98 Fa/fa) were used. Dietary induced obesity (DIO) was...
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