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Article

The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue.

Diabetes/metabolism research and reviews - 1 Jan 2000

Klöting Nora, Blüher Matthias, Klöting Ingrid

Abstract excerpt

BACKGROUND: Wistar Ottawa Karlsburg W (RT1u) rats (WOKW) develop a complete metabolic syndrome closely resembling the human disease. The aim of this study was to characterize the phenotype of adipose tissue in WOKW rats with regard to adipocyte metabolism, insulin resistance, and gene expression and thus to define the phenotype more precisely. METHODS: Glucose metabolism, insulin sensitivity, and gene expression...

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PMID: 16041833
DOI: 10.1002/dmrr.582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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