Pre-pubertal diet restriction reduces reactive oxygen species and restores fertility in male WNIN/Obese rat.

doi:10.1111/and.12849

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Article

Pre-pubertal diet restriction reduces reactive oxygen species and restores fertility in male WNIN/Obese rat.

Andrologia - 1 Mar 2018

Dinesh Yadav D M, Muralidhar M N, Prasad S M V K, Rajender Rao K

Abstract excerpt

Obesity is a multifactorial disorder associated with increased body adiposity, chronic oxidative stress which contributes to impaired fertility in males. Diet restriction and anti-oxidant supplementations are known to protect obese subjects from oxidative stress and improves fertility. However, the role of oxidative stress and the age of intervention in restoring male fertility are poorly understood. This study...

Topics

Age Factors
Animals
Body Composition
Caloric Restriction
Disease Models, Animal
Female
Humans
Infertility, Male
Male
Mutation
Obesity
Oxidative Stress
Puberty
Rats
Rats, Transgenic
Reactive Oxygen Species
Sexual Maturation

Source

Open in PubMed

Identifiers

PMID: 28718974
DOI: 10.1111/and.12849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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