Article
Functional assay of a putative Drosophila sodium channel gene in homozygous deficiency neurons.
Journal of neurogenetics - 1 Feb 1992
Germeraad S, O'Dowd D, Aldrich R W
Abstract excerpt
Using voltage-clamp techniques, we have examined embryonic sodium currents in neurons deficient for a gene located at 60E5/6 that shares extensive amino acid similarity with vertebrate sodium channel genes. These neurons expressed sodium currents similar to wildtype, supporting the hypothesis that para, and not the gene at 60E5/6, is the primary sodium channel gene expressed in embryonic neurons. A simple marking...
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