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Article

Effect of sodium channel abundance on Drosophila development, reproductive capacity and aging.

Fly - 1 Jan 2000

Garber Graham, Smith Lee Ann, Reenan Robert A, Rogina Blanka

Abstract excerpt

The voltage-gated Na (+) channels (VGSC) are complex membrane proteins responsible for generation and propagation of the electrical signals through the brain, the skeletal muscle and the heart. The levels of sodium channels affect behavior and physical activity. This is illustrated by the maleless mutant allele (mle (napts)) in Drosophila, where the decreased levels of voltage-gated Na(+) channels cause...

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Identifiers

PMID: 22513411
DOI: 10.4161/fly.18570
PMCID: PMC3365838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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