Article
Cloning and functional analysis of TipE, a novel membrane protein that enhances Drosophila para sodium channel function.
Cell - 22 Sept 1995
Feng G, Deák P, Chopra M, Hall L M
Abstract excerpt
Voltage-dependent sodium channels are involved in the initiation and propagation of action potentials in many excitable cells. Here we report that tipE, a gene defined by a temperature-sensitive paralytic mutation in Drosophila, encodes a novel integral membrane protein that dramatically stimulat...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Codon, Terminator
- DNA, Complementary
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Genes, Insect
- Hot Temperature
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Oocytes
- Paralysis
- Pupa
- Sodium Channels