Article
Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitability.
Genetics - 1 Jan 1990
Stern M, Kreber R, Ganetzky B
Abstract excerpt
The effects of para mutations on behavior and axonal excitability in Drosophila suggested that para specifically affects sodium channels. This hypothesis was confirmed by molecular analysis of the para locus, which demonstrates that the encoded para product is a sodium channel polypeptide. Here we characterize the effects of altered para+ dosage on behavior and axonal excitability, both in an otherwise wild-type...
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