Article
Proteome phenotyping of ΔrelA mutants in Enterococcus faecalis V583.
Canadian journal of microbiology - 1 Aug 2014
Yan Xue, Budin-Verneuil Aurélie, Auffray Yanick, Pichereau Vianney
Abstract excerpt
The (p)ppGpp synthetase RelA contributes to stress adaptation and virulence in Enterococcus faecalis V583. A 2-dimensional electrophoresis proteomic analysis of 2 relA mutants, i.e., ΔrelA carrying a complete deletion of the relA gene, and ΔrelAsp that is deleted from only its 3' extremity, showed that 31 proteins were deregulated in 1 or both of these mutants. Mass spectrometry identification of these proteins...
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