Article
Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene.
Addiction biology - 1 Sept 2003
McQuade John-Andrews, Xu Ming, Woods Stephen C, Seeley Randy J, Benoit Stephen C
Abstract excerpt
Considerable evidence suggests that the mesolimbic dopaminergic system is an important substrate for the rewarding effects of ethanol consumption. Previous data have demonstrated that pharmacological agents that alter dopamine signaling also influence the self-administration of ethanol. The present experiments were designed to assess the role of the dopamine-3 receptor (D3-R) on voluntary ethanol consumption in...
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