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Article

Fine specificity and MHC restriction of trinitrophenyl-specific CTL.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 1999

Franco A, Yokoyama T, Huynh D, Thomson C, Nathenson S G, Grey H M

Abstract excerpt

In this study, the fine specificity and MHC restriction of a CTL response specific to the trinitrophenyl (TNP) hapten was analyzed. Based on the structure of peptide/Kb complexes and ternary TCR/Ag/MHC complexes, four TNP peptides, two octamers, and two nonamers were chosen for eliciting anti-TNP CTL responses. Hapten was conjugated at position 4 in the octamers and at position 5 in the nonamers, positions which...

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PMID: 10092793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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