T cells with dual antigen specificity in T cell receptor transgenic mice rejecting allografts.

doi:10.1002/eji.1830251015

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Article

T cells with dual antigen specificity in T cell receptor transgenic mice rejecting allografts.

European journal of immunology - 1 Oct 1995

Simpson E, Chandler P, Sponaas A, Millrain M, Dyson P J

Abstract excerpt

Allelic exclusion of T cell receptor (TCR) genes is incomplete: a significant percentage (10-30%) of normal human and mouse peripheral T cells express two surface TCR alpha chains, and a small percentage of peripheral human T cells have been reported to express two surface TCR beta chains. A prop...

Topics

Alleles
Amino Acid Sequence
Animals
Antigens, Viral
Base Sequence
Female
Flow Cytometry
Gene Rearrangement, T-Lymphocyte
Graft Rejection
H-2 Antigens
H-Y Antigen
Lymphocyte Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Mice, Inbred AKR

Mice, Inbred BALB C

Mice, Inbred C57BL

Mice, Transgenic

Source

Open in PubMed

Identifiers

PMID: 7589076
DOI: 10.1002/eji.1830251015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7589076-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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