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Article

T cells with dual antigen specificity in T cell receptor transgenic mice rejecting allografts.

European journal of immunology - 1 Oct 1995

Simpson E, Chandler P, Sponaas A, Millrain M, Dyson P J

Abstract excerpt

Allelic exclusion of T cell receptor (TCR) genes is incomplete: a significant percentage (10-30%) of normal human and mouse peripheral T cells express two surface TCR alpha chains, and a small percentage of peripheral human T cells have been reported to express two surface TCR beta chains. A proportion of thymocytes in TCR transgenic mice rearrange endogenous T cell receptor genes, and peripheral T cells with two...

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PMID: 7589076
DOI: 10.1002/eji.1830251015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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