Article
A baculovirus mutant defective in PKIP, a protein which interacts with a virus-encoded protein kinase.
Virology - 5 Jul 1998
McLachlin J R, Yang S, Miller L K
Abstract excerpt
We have found that a temperature-sensitive mutant of the baculovirus AcMNPV, tsB97, is defective in PKIP, the product of ORF24 which was previously found to interact with and stimulate the activity of a virus-encoded protein kinase, PK-1. The mutant lacks the ability to form plaques and occlusion...
Topics
- Animals
- Blotting, Northern
- Carrier Proteins
- Cell Line
- Chromosome Mapping
- DNA, Viral
- Gene Deletion
- Gene Expression Regulation, Viral
- Microscopy, Electron
- Nucleopolyhedroviruses
- Phenotype
- Phosphorylation