G-protein oncogenes in acromegaly.

doi:10.1159/000182498

Back to search

Article

G-protein oncogenes in acromegaly.

Hormone research - 1 Jan 1992

Spada A, Vallar L

Abstract excerpt

G-proteins belong to a family of proteins which share the common properties of GTP binding and hydrolysis. Heterotrimeric G-proteins are composed of alpha-, beta- and gamma-subunits. The alpha-subunit which differs from one G-protein to another contains the GDP/GTP binding site and has intrinsic...

Topics

Acromegaly
Adenoma
GTP-Binding Proteins
Growth Hormone
Humans
Mutation
Oncogenes
Pituitary Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.