Article
Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients.
European journal of endocrinology - 1 Jun 1996
Yang I, Park S, Ryu M, Woo J, Kim S, Kim J, Kim Y, Choi Y
Abstract excerpt
A subset of human growth hormone (GH)-secreting pituitary tumors contains the gsp oncogene that encodes an activation mutation of the alpha-subunit of the stimulatory GTP-binding protein (G(S) alpha). This study was undertaken to investigate the frequency of the gsp oncogene in GH-secreting pitui...
Topics
- Acromegaly
- Adult
- Aged
- Aging
- Alleles
- Female
- GTP-Binding Proteins
- Growth Hormone
- Humans
- Korea
- Male
- Middle Aged
- Mutation
- Oncogenes
- Pituitary Neoplasms
- Polymerase Chain Reaction