Article
Characteristics of gsp-positive growth hormone-secreting pituitary tumors in Korean acromegalic patients.
European journal of endocrinology - 1 Jun 1996
Yang I, Park S, Ryu M, Woo J, Kim S, Kim J, Kim Y, Choi Y
Abstract excerpt
A subset of human growth hormone (GH)-secreting pituitary tumors contains the gsp oncogene that encodes an activation mutation of the alpha-subunit of the stimulatory GTP-binding protein (G(S) alpha). This study was undertaken to investigate the frequency of the gsp oncogene in GH-secreting pituitary tumors in Korean acromegalic patients and to elucidate the clinical characteristics of these patients to endocrine...
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