Article
The molecular basis of disorders caused by defects in G proteins.
Hormone research - 1 Jan 1997
Spiegel A M
Abstract excerpt
G proteins couple receptors for many hormones to effectors that regulate second messenger metabolism. G protein dysfunction could involve gain or loss of function. For Gs, the G protein that couples receptors to stimulation of cAMP formation, examples of both types have already been defined. Germ...
Topics
- Acromegaly
- Cyclic AMP
- Fibrous Dysplasia, Polyostotic
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Humans
- Hyperthyroidism
- Molecular Structure
- Mutation
- Night Blindness
- Protein Conformation
- Pseudohypoparathyroidism