Mutations of signal-transducing G proteins in human disease.

doi:10.1007/BF00189921

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Article

Mutations of signal-transducing G proteins in human disease.

Journal of molecular medicine (Berlin, Germany) - 1 May 1995

Schnabel P, Böhm M

Abstract excerpt

Heterotrimeric guanine nucleotide binding proteins (G proteins) couple a large number of cell surface receptors to their intracellular effector molecules, such as enzymes or ion channels. Mutations of G proteins can lead to either activation or inactivation of the corresponding signal transductio...

Topics

Amino Acid Sequence
Base Sequence
Endocrine Gland Neoplasms
Fibrous Dysplasia, Polyostotic
GTP-Binding Proteins
Humans
Molecular Sequence Data
Mutation
Pseudohypoparathyroidism
Puberty, Precocious
Signal Transduction

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