Article
[G-proteins and endocrine tumors. The example of acromegaly].
La Revue du praticien - 1 May 1994
Chabre O
Abstract excerpt
Mutations of Gs are found in 30 to 40% of the pituitary tumours responsible for acromegaly (somatotrope tumor), 10% of secreting thyroid tumors, and in the rare McCune-Albright syndrome. Gs is a member of the G protein family, which plays a major role in the mechanism of action of many hormones b...
Topics
- Acromegaly
- Cell Transformation, Neoplastic
- Endocrine Gland Neoplasms
- GTP-Binding Proteins
- Humans
- Mutation
- Oncogenes