Article
Epidemiological models of carcinogenesis: the example of bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
Vineis P
Abstract excerpt
Epidemiological studies have clearly shown that smokers have an increased risk of bladder cancer. Chemical, biochemical, and molecular investigations indicate that such risk might be due to aromatic amines which are present in tobacco smoke. In particular, collaborative studies have shown that smokers have increased levels of hemoglobin-4-aminobiphenyl adducts in their blood and that these levels show a...
Topics
- Acetylation
- Adolescent
- Adult
- Age Factors
- Amines
- Humans
- Models, Statistical
- Occupational Exposure
- Phenotype
- Polymorphism, Genetic
- Risk Factors