Article
[Aromatic amines, oncogenes and cancer of the bladder].
Medycyna pracy - 1 Jan 1991
Lutz W, Krajewska B
Abstract excerpt
The role of aromatic amines in cancer inducing is mainly connected with their metabolism in the organism. During successive cell changes certain adducts are generated which may bind DNA. Their ability to cause mutations depends on whether a given adduct was generated with a free form or an acetylated amine. Adducts generated with non-acetylated amines are the main cause of mutations, i.e. changes of base in a...
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