Article
The use of 4-aminobiphenyl hemoglobin adducts and aromatic DNA adducts in lymphocytes of smokers as biomarkers of exposure.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 1998
Dallinga J W, Pachen D M, Wijnhoven S W, Breedijk A, van 't Veer L, Wigbout G, van Zandwijk N, Maas L M, van Agen E, Kleinjans J C, van Schooten F J
Abstract excerpt
Two biomarkers of exposure to cigarette smoke, 4-aminobiphenyl-hemoglobin (Hb) adducts and aromatic DNA adducts in lymphocytes, were determined from a population of 55 smokers and 4 nonsmokers. The levels of these adducts were related to daily cigarette consumption and also to (calculated) tar an...
Topics
- Adult
- Aminobiphenyl Compounds
- Arylamine N-Acetyltransferase
- Biomarkers
- DNA Adducts
- Female
- Glutathione Transferase
- Hemoglobin A
- Humans
- Lymphocytes
- Male
- Phenotype
- Polymorphism, Genetic