Article
Acetylation phenotype, carcinogen-hemoglobin adducts, and cigarette smoking.
Cancer research - 15 May 1990
Vineis P, Caporaso N, Tannenbaum S R, Skipper P L, Glogowski J, Bartsch H, Coda M, Talaska G, Kadlubar F
Abstract excerpt
Levels of 4-aminobiphenyl-hemoglobin adducts in smokers of blonde (flue-cured) and black (air-cured) tobacco have been found to be proportional to bladder cancer risk. In addition, risk of bladder cancer due to exposure to occupational carcinogens is elevated in genetically determined slow acetylators. In this study of normal male volunteers, 4-aminobiphenyl-hemoglobin adducts were found to be related to both the...
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