Article
Amino acid sequence of fibrolase, a direct-acting fibrinolytic enzyme from Agkistrodon contortrix contortrix venom.
Protein science : a publication of the Protein Society - 1 May 1992
Randolph A, Chamberlain S H, Chu H L, Retzios A D, Markland F S, Masiarz F R
Abstract excerpt
The complete amino acid sequence of fibrolase, a fibrinolytic enzyme from southern copperhead (Agkistrodon contortrix contortrix) venom, has been determined. This is the first report of the sequence of a direct-acting, nonhemorrhagic fibrinolytic enzyme found in snake venom. The majority of the sequence was established by automated Edman degradation of overlapping peptides generated by a variety of selective...
Topics
- Amino Acid Sequence
- Amino Acids
- Animals
- Crotalid Venoms
- Cyanogen Bromide
- Endopeptidases
- Genetic Variation
- Metalloendopeptidases
- Molecular Sequence Data
- Peptides
- Protein Structure, Secondary