Article

Mapping specificity, entropy, allosteric changes and substrates in blood proteases by a high-throughput protease screen

2020-07-21

Abstract excerpt

Proteases are among the largest protein families in eukaryotic phylae with more than 500 genetically encoded proteases in humans. By cleaving a wide range of target proteins, proteases are critical regulators of a vast number of biochemical processes including apoptosis and blood coagulation. Over the last 20 years, knowledge of proteases has been drastically expanded by the development of proteomic approaches to...

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Identifiers and source

Literature Corpus work: 488374ed-62c3-5850-9b91-0732a8ae9bad
DOI: 10.1101/2020.07.20.211524

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