Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere maintenance is dependent on activities required for end repair of double-strand breaks.

Current biology : CB - 21 May 1998

Nugent C I, Bosco G, Ross L O, Evans S K, Salinger A P, Moore J K, Haber J E, Lundblad V

Abstract excerpt

Telomeres are functionally distinct from ends generated by chromosome breakage, in that telomeres, unlike double-strand breaks, are insulated from recombination with other chromosomal termini [1]. We report that the Ku heterodimer and the Rad50/Mre11/Xrs2 complex, both of which are required for r...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to DNA, Fungal
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Mutation

Share to Nuclear Proteins

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Identifiers

PMID: 9635193
DOI: 10.1016/s0960-9822(98)70253-2

Genes

MRE11
RAD50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9635193-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere maintenance is dependent on activities required for end repair of double-strand breaks.PMID 9635193Read ↗

A quantitative assay for telomere protection in Saccharomyces cerevisiae.Semantic proximity Read ↗

The Ku heterodimer performs separable activities at double-strand breaks and chromosome termini.Semantic proximity Read ↗

Telomere dysfunction in genome instability syndromes.Semantic proximity Read ↗

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends.Semantic proximity Read ↗

Yeast Ku as a regulator of chromosomal DNA end structure.Semantic proximity Read ↗

Telomeres and the DNA damage response: why the fox is guarding the henhouse.Semantic proximity Read ↗

To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand BreaksSemantic proximity Read ↗

Evolution of CST function in telomere maintenanceSemantic proximity Read ↗

Role of the ESCRT Complexes in Telomere Biology.Semantic proximity Read ↗

Telomere shortening triggers a feedback loop to enhance end protection.Semantic proximity Read ↗

Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forksSemantic proximity Read ↗

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.