Article
Point mutation in the parkin gene on patients with Parkinson's disease.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Jan 2003
Wang Tao, Liang Zhihou, Sun Shenggang, Cao Xuebing, Peng Hai, Cao Fei, Liu Hongjin, Tong E-tang
Abstract excerpt
To investigate the distribution of possible novel mutations from parkin gene in variant subset of patients with Parkinson's disease (PD) in China and explore whether parkin gene plays an important role in the pathogenesis of PD, 70 patients were divided into early-onset group and late-onset group; 70 healthy subjects were included as controls. Genomic DNA from 70 normal controls and from those of PD patients were...
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